However, conjugated drugs cannot easily leave the capillary, only unbound drugs can be distributed into tissues, thus exerting pharmacological activity or toxicity. For example, binding to serum albumin increases the solubility of lipophilic drugs, allowing them to reach the site of action.
The binding with serum albumin has great influence on the pharmacokinetics and pharmacodynamics of most commonly used prescription drugs. Albumin also plays a role in protecting ischemic and hypoxic liver injury, mainly due to its strong antioxidant characteristics.Īs a carrier of drugs, serum albumin reversibly binds to most drugs in the blood circulation. Egg allergies disproportionately affect children.Īlbumin can be widely used as a plasma volume extender in many clinical conditions, such as hypovolemic, shock, burn, surgery, trauma, acute respiratory distress syndrome, hemodialysis, acute liver failure, hypoalbuminosis, etc.
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The main symptoms of egg allergies including: skin allergies, such as hives or rashes nausea, diarrhea, stomach pain, and vomiting throat, lips, tongue, or facial swelling to wheezing, coughing, or a runny nose. The symptoms are common in people who are in frequent contact with birds and may be sensitive to proteins in bird bird's feathers, droppings, or dander that can cause the development of an allergy to eggs (It's primarily an allergy to chicken albumin). This is an allergy related to chicken serum albumin. It means that some people may develop an allergy to eggs after developing an allergy to birds. The role of serum albumin in cardiovascular disease is important for understanding the prognostic value of serum albumin in total cardiovascular disease (CVD).Ī special kind of disease related to serum albumin, called Bird-Egg Syndrome. Moreover, the increase in all-cause mortality and cardiovascular (CV) mortality is associated with low serum albumin concentration, serum albumin has traditionally been considered a biomarker for reliable risk prediction in various clinical settings. In addition, familial dysalbuminemic hyperthyroxinemia and familial dysalbuminemic hypertriiodothyroninemia syndromes, an autosomal dominant genetic disease, are also caused by the mutation of HSA.įamilial hyperzincemia is caused by the increased ability of HSA to bind to Zn (II), the main transporter of Zn (II) in blood, a metal ion required by a physiological process, which is absorbed by various drugs and toxins. When persistent and unexplained hypoalbuminemia was observed, the diagnosis was hypothesized to be aplastic and confirmed by the absence of the HSA bands in the plasma protein electrophoresis pattern. One is analbuminemia, a very rare recessive genetic disorder, in which HSA either does not exist or is significantly reduced.
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